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This study, a systematic review and meta-analysis of 39 randomized clinical trials with 10,761 participants, found no evidence of an increased risk of suicide or attempted suicide, suicidal ideation, depression or death with varenicline. The authors did acknowledge that the drug could cause insomnia and abnormal dreams, side effects that were already well recognized

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Within hours, suction can dislodge protective blood clots, causing dry socket in 20-30% of smokers versus 2-5% of non-smokers

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